

DNA image on cover: majcot/Shutterstock DNA image on chapter and section opener pages: Mopic/Shutterstock Section opener images: mouse, Sergey Galushko/Shutterstock lab equipment, Vasiliy Koval/Shutterstock vaccine, Nixx Photography/Shutterstock Some igures and tables in this book are reprinted or modiied from Glick et al., Molecular Biotechnology: Principles and Applications of Recombinant DNA, 4th ed. Courtesy of Anupriya Aggarwal and Stuart Turville (Kirby Institute, University of New South Wales). Reproduced from the cover of PLoS Pathogens, June 2012. Box 605, Herndon, VA 20172, USA Phone: (800) 546-2416 or (703) 661-1593 Fax: (703) 661-1501 Online: doi:10.1128/9781555818890 Cover and interior design: Susan Brown Schmidler Illustrations: Patrick Lane, ScEYEnce Studios Image credits for cover and section openers Cell image on cover: A dendritic cell infected with human immunodeiciency virus (HIV), showing projections called ilopodia (stained red) with HIV particles (white) at their ends. NW, Washington, DC 20036-2904, USA E-mail: Send orders to ASM Press, P.O. TP248.2.G57 2014 660.6-dc23 2013027259 10 9 8 7 6 5 4 3 2 1 Printed in the United States of America Address editorial correspondence to ASM Press, 1752 N St.

pages cm Includes bibliographical references and index. Patten, Biology Department, University of New Brunswick, Fredericton, New Brunswick, Canada. Delovitch, Department of Microbiology and Immunology, Western University, London, Ontario, Canada Cheryl L. Glick, Department of Biology, University of Waterloo, Waterloo, Ontario, Canada Terry L. Library of Congress Cataloging-in-Publication Data Glick, Bernard R., author. The views and opinions of the author(s) expressed in this publication do not necessarily state or relect those of ASM, and they shall not be used to advertise or endorse any product. Any reference herein to any speciic commercial products, procedures, or services by trade name, trademark, manufacturer, or otherwise does not constitute or imply endorsement, recommendation, or favored status by the American Society for Microbiology (ASM).
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No part of this publication may be reproduced or transmitted in whole or in part or reused in any form or by any means, electronic or mechanical, including photocopying and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Patten Biology Department University of New Brunswick Fredericton, New Brunswick, CanadaĬopyright © 2014 American Society for Microbiology. Delovitch Department of Microbiology and Immunology Western University London, Ontario, CanadaĬheryl L. Glick Department of Biology University of Waterloo Waterloo, Ontario, Canada
